Publications Michael Basler

  1. Froeschke M, Basler M, Groettrup M, Dobberstein B. 2003. Long-lived signal peptide of lymphocytic choriomeningitis virus glycoprotein pGP-C. J Biol Chem 278(43):41914-20.
  2. Probst HC, Tschannen K, Gallimore A, Martinic M, Basler M, Dumrese T, Jones E, van den Broek MF. 2003. Immunodominance of an antiviral cytotoxic T cell response is shaped by the kinetics of viral protein expression. J Immunol 171(10):5412-22.
  3. Khan S, Zimmermann A, Basler M, Groettrup M, Hengel H. 2004. A cytomegalovirus inhibitor of gamma interferon signaling controls immunoproteasome induction. J Virol 78(4):1831-42.
  4. Basler M, Youhnovski N, van den Broek M, Przybylski M, Groettrup M. 2004. Immunoproteasomes downregulate presentation of a subdominant T cell epitope from lymphocytic choriomeningitis virus. J Immunol 173(6):3925-34.
  5. Basta S, Stoessel R, Basler M, van den Broek M, Groettrup M. 2005. Cross-presentation of the long-lived lymphocytic choriomeningitis virus nucleoprotein does not require neosynthesis and is enhanced via heat shock proteins. J Immunol 175(2):796-805.
  6. Basler M, Moebius J, Elenich L, Groettrup M, Monaco JJ. 2006. An altered T cell repertoire in MECL-1-deficient mice. J Immunol 176(11):6665-6672.
  7. Basler M, Groettrup M. 2007. Advances in prostate cancer immunotherapies. Drugs Aging 24(3):197-221.
  8. Basler M, Groettrup M. 2007. No essential role for tripeptidyl peptidase II for the processing of LCMV-derived T cell epitopes. Eur J Immunol 37(4):896-904.
  9. Muchamuel T*, Basler M*, Aujay MA, Suzuki E, Kalim KW, Lauer C, Sylvain C, Ring ER, Shields J, Jiang J, Shwonek P, Parlati F, Demo SD, Bennett MK, Kirk CJ , Groettrup M. 2009. A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. Nat Med 15(7):781-787. * shared first authorship
  10. Basler M, Lauer C, Beck U, Groettrup M. 2009. The proteasome inhibitor bortezomib enhances the susceptibility to viral infection. J Immunol 183(10):6145-6150.
  11. Groettrup M, Kirk CJ, Basler M. 2010. Proteasomes in immune cells: more than peptide producers? Nat Rev Immunol 10(1):73-78.
  12. Basler M, Dajee M, Moll C, Groettrup M, Kirk CJ. 2010. Prevention of experimental colitis by a selective inhibitor of the immunoproteasome1.J Immunol 185(1):634-641.
  13. Kremer M, Henn A, Kolb C, Basler M, Moebius J, Guillaume B, Leist M, Van Den Eynde BJ, Groettrup M. 2010. Reduced immunoproteasome formation and accumulation of immunoproteasomal percursors in the brain of LCMV-infected mice. J Immunol 185(9):5549-60.
  14. Moebius J, Van den Broek M, Groettrup M, Basler M. 2010. Immunoproteasomes are essential for survival and expansion of T cells in virus infected mice. Eur J Immunol 40(12):3439-49.
  15. Sommershof A, Basler M, Riether C, Engler H, Groettrup M. 2010. Attenuation of the cytotoxic T lymphocyte response to lymphocytic choriomeningitis virus in mice subjected to chronic social stress. Brain Behav Immun 5(2):340-348.
  16. Basler M, Beck U, Kirk CC, Groettrup M. 2011. The antiviral immune response in mice devoid of immunoproteasome activity. J Immunol 187(11):5548-5557.
  17. Huber EM*, Basler M*, Schwab R*, Kirk CJ, Heinemeyer W, Groettrup M, Groll M. 2012. Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity. Cell 148(4):727-738. * shared first authorship
  18. Basler M, Groettrup M. 2012. Immunoproteasome-specific inhibitors and their application. Methods Mol Biol 832:391-401.

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Biotechnology Institute Thurgau
at the University of Constance
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